Why does it say "l'Mi Oy l'Mi Avoy"?
Rashi: They are expressions of screaming and wailing. R. Yonah - they are due to his sin. Wine brings a person to Zenus. Therefore this is written next to Zonah and Nochriyah.
Malbim: Who has woe? One who has Avoy (desire).
What do we learn from "[l'Mi Oy l'Mi Avoy] l'Mi Midyanim l'Mi Si'ach"?
Rashi: One who has quarrels with people and excess talk, woe to him - in many words, there is much sin.
R. Yonah: Wine causes also quarrels and excess talk - "Homeh Shechar" (20:1).
Malbim: Who has quarrels and claims? One who has Si'ach - speech without intellect. He merely casts out (says) imaginations. This increases quarrels.
What are "Petza'im Chinam"?
R. Yonah: Drinking much wine leads to bodily illnesses.
Why does it say "[l'Mi Petza'im Chinam l'Mi] Chachlilus Einayim"?
Rashi: Amidst much wine, the eyes redden. This is derogatory.
Malbim: One who has red eyes [from much wine] he has wounds. Who has red eyes? ("Ha'Me'acharim Al ha'Yayin" - 30)
What do we learn from "l'Mi Oy l'Mi Avoy l'Mi Midyanim l'Mi Si'ach l'Mi Petza'im Chinam l'Mi Chachlilus Einayim"?
Sanhedrin 70a #1: "La'Me'acharim Al ha'Yayin" (30, people who drink much wine) suffer all these.
Sanhedrin 70a #2: Some expound it in reverse order (one who suffers all these should indulge in wine).
