Why does it say "Dirshu Hashem v'Uzo"?
Gra (Divrei ha'Yamim I, 16:11): Who should seek Hashem? One who knows His Midos 1 and the Midos of the Torah, which is called Uzo. This is why it says after this "Bakshu Fanav."
Malbim: Seeking is primary, and not finding. No one will grasp Hashem Himself, just one must seek His deeds; this is the purpose.
Hagahah from the Gra's grandson: This corresponds to Brachos 32a 'one should arrange Hashem's praise, and then pray (request).'
What is "Uzo"?
Radak: The Aron is called Oz - "va'Yiten la'Shevi Uzo" (78:61). Seek the Mishkan (dwelling place) of the Aron, and there pray in front of Him.
'Rashi' (Divrei ha'Yamim I, 16:11): The Mikdash and Aron are called Uzo - "va'Yiten la'Shevi Uzo" (78:61). He let the Aron be captured, and it says "Kumah Hashem li'Mnusecha Atah va'Aron Uzecha" (132:8). Elazar was called Uza, for he guarded the Aron, which is called Oz. We find [names connected to actions of the person, e.g.] the Gematriya of Efron is 400 (the amount he requested for Me'aras ha'Machpelah), "Dan Yadin Amo", "Yehudah Yoducha Achecha" (Bereishis 49:16, 8).
What is the meaning of "Bakshu Fanav [Tamid]"?
Radak: Pray in front of Him.
Radak citing Shocher Tov: To see the Shechinah in this world, engage in Torah in Eretz Yisrael. The Shechinah is there; there, Tefilah will be accepted quickly.
Malbim: Whatever you will understand of Him, you will understand that you did not understand, and you must seek more - "Yelchu me'Chayil El Chayil" (84:8).