What is "l'Fach ul'Mokesh"?
Malbim: You will stumble in matters of Torah and Emunah.
What is "Leshotet b'Tzideichem"?
Rashi: [The Kena'anim] will go plundering around you.
Radak: It is a stick [to hit you], like "Shot la'Sus" (Mishlei 26:3).
What are "Tzeninim"?
Rashi: They are [army] camps, like "u'Va'u Alecha Hotzen" (Yechezkel 23:24); it is like a shield that surrounds on three sides
Is this punishment natural, or supernatural?
Malbim: Our verse discusses a natural punishment. You will not be able to have full love and a true covenant with them. Even at a tranquil time, they will gouge out your eyes through envy and hatred. The next verses foretell evil that will befall you via Hashgachah.