Rashi: It (R. Yonah - Chachmah, Tevunah and Da'as) should not be crooked in front of your eyes, to remove it from being in front of you. R. Yonah #1 - after I informed you of their great praise - Shamayim va'Aretz were made from them, you must contemplate this matter. Lower and upper beings cannot distinguish between the myriads of ways of His Chachmah. Creations do not know how to create even a fly!

R. Yonah #2: Everything that man attains from Chachmah is a great matter, since "b'Chachmah Yasad Aretz" (19).

R. Yonah #3: It comes to warn about guarding the Torah. Since you know that "b'Chachmah Yasad Aretz", you should know that His Torah is refined and pure. The actions that He chose are the choice actions, "Asher Ya'aseh Osam ha'Adam va'Chai Bahem" (Vayikra 18:5), "Imros Hashem Imros Tehoros" (Tehilim 12:7). First it warned about Chesed, Emes, Bitachon and fear, for via fixing the intents, the deeds are accepted - "Niru Lachem Nir v'Al Tizre'u El Kotzim; Himolu la'Shem" (Yirmeyah 4:3-4). Now it warns about guarding the entire Torah. Refer to 4:21:1:1 and the note there.

Malbim: The ways of Chachmah should not veer from your inner eyes, i.e. of the heart. Refer to 4:21:2:2.

R. Yonah #1: The Torah, which is called Tushiyah (Sanhedrin 26b) and Mezimah.

R. Yonah #2: Chukim are called Tushiyah, and Mitzvos that Sechel grasps are called Mezimah. Tushiyah is an expression of foundation - "v'Ushaya Yachitu" (Ezra 4:12). Its grammatical form is like "Tufini" (Vayikra 6:14).

Malbim: Mezimah are deep thoughts in Chachmah. Tushiyah are deeds done based on Chachmah. Guard that your deeds, investigation and thoughts are all according to the ways of Chachmah. It is not enough to be careful about deeds. Learning brings to deed; an ignoramus cannot be a Chasid, and a Bur cannot fear sin.