What is "Am No'az"?
Rashi: This is like Lo'ez. They are Ashur and Bavel; their language is not Leshon ha'Kodesh.
Radak: Refer to 33:19:2:2. No'az is like Az (brazen). Kasdim (Bavel) are the brazen nation.
What is the meaning of "Lo Sir'eh"?
Rashi: Do not esteem them in your heart. All of them will be dark and lowly.
Radak: You will no longer see the ones who count [and collect the tax].
What is the meaning of "Es Am No'az Lo Sir'eh Am Imkei Safah"?
Rashi (17): Such a nation will not see the Shechinah of the King in His beauty.
Malbim: You will no longer see Sancheriv's strong nation; they will perish.
Who are "Imkei Safah" and "Nil'ag Lashon"?
Rashi: People who do not know Leshon ha'Kodesh.
Radak: Imkei Safah means that they spoke Arame'ic, which only individuals of Yisrael understood. Elyakim, Shevna and Yo'ach told Ravshake "speak to your servants in Arame'ic, and do not speak in Yehudis in the ears of this nation" (36:11). One who does not understand a language, to him it is Amok and Nil'ag - "b'La'agei Safah uv'Lashon Acheres" (28:11).
What is the meaning of "mi'Shmo'a"?
Radak: They do not understand. This is like "Goy Asher Lo Sishma Leshono" (Devarim 28:49). Also "Ein Binah" means so; the matter is repeated in different words.