Why did he say "Kamah Sir'eh"?
Rashi: How much patience do You have to see all this?!
Radak: How long will You see my affliction and oppression from them?! This is like "Kamah Ner Resha'im Yid'ach" (Iyov 21:17).
Malbim: Even though I did not know their intent, that they come to jest and mock, You see everything!
What is the meaning of "Hashivah Nafshi"?
Radak: This is saving, like "Amar Hashem mi'Bashan Ashiv Ashiv mi'Metzulos Yam" (68:23).
Malbim: Save my Nefesh - in any case I am in danger! If I am among people, I am in danger from their tumult - save me from this! If I separate from them to be isolated in Midbaros, I am in danger from the lions there - save me from them!
What is "mi'Sho'eihem"?
Rashi: From their darkness.
Radak: Their tumult and turmoil.
What is the meaning of "mi'Kefirim Yechidasi"?
Rashi: This refers back to "Hashivah Nafshi"; return my Neshamah from the young lions [who seek to kill me].