What do we learn from "Kir'u Zos"?
Radak: It is as if an announcement goes out and arouses them to come to this war against Yerushalayim.
Malbim: This returns to above. He will gather all the Goyim to Emek Yehoshafat (2). I explained in Yechezkel that the nations of Edom will be aroused to conquer Eretz Yisrael. They will kill many in Egypt who have the creed of Yishmael. The Yishmaelim will be aroused to avenge this, and will kill many of Edom. Edom will be aroused, and will kill many of Yishmael. Three times there will be war of Gog and Magog in the end of days. The first time, the Giborim who know war strategy will fight.
Why does it say "Kadeshu Milchamah"?
Rashi: If you can fight against Me [prepare for war]! Radak - Kadeshu is summonsing, like "va'Ykadesh Es Yishai v'Es Banav" (Shmuel I, 16:5).