Why did Hashem now speak to Aharon as well?
Rashi and Ramban: Because, following Moshe's complaint regarding his speech defect, Hashem sent Aharon together with him to act as his spokesman. 1
What does the Torah mean when it writes that He commanded them regarding the Bnei Yisrael and regarding Pharaoh ... ?
Rashi #1: He commanded them to lead Yisrael gently; and to address Pharaoh with respect. 1
Rashi #2 and Ramban #1 (citing the Ibn Ezra): He commanded them with regard to the matters concerning Yisrael and his Shelichus to Pharaoh, which the Torah will present later (from Pasuk 6:29 and onwards).
Rashi #3 (to Bamidbar 11:12): He commanded him to bear Yisrael, even to the point that they threaten to stone him and insult him. 2
Ramban #2 (to 6:12): The Pasuk means that Moshe and Aharon should speak to Yisrael and tell them whatever Hashem would command them; and Pharaoh to send Yisrael out of his land.
Seforno: It means that Hashem appointed Moshe and Aharon princes 3 over Yisrael and over Pharaoh - creating an aura of Divine authority that forced Yisrael and Pharaoh to obey their every command concerning the redemption.
Moshav Zekenim (to 6:12): It means that Hashem commanded Bnei Yisrael to leave Egypt, and Pharaoh to expel them, even if they do not want to leave.
Hadar Zekenim: It means that Hashem commanded them to go to Pharaoh on behalf of Klal Yisrael, 4 and order him to expel them.
Yerushalmi Rosh Hashanah (3:5): Following Pasuk 6:11, Hashem instructed Moshe and Aharon to teach Yisrael the Dinim concerning sending away one's Eved Ivri after six years. 5
Gur Aryeh: Why does Rashi digress from the simple meaning; and how can this interpretation be read into the Pasuk? See 6:13:2.1:1, 6:13:2.2:1, and 6:13:2.3:1.
Oznayim la'Torah: Which they must accept without being fazed - a major lesson in leadership. And this is followed by the Yichus of Reuven, Shimon and Levi, the three tribes that produced the three people who caused Moshe the most trouble - Dasan and Aviram from Reuven, Zimri from Shimon and Korach from Levi.
Seforno: As in Bamidbar 27:23, and Shmuel I 25:30.
This is also how Rashi explains it, in Rashi to Bereishis 50:16.
(These Dinim are found in Shemos 21) see Torah Temimah, notes 11 and 12.
QUESTIONS ON RASHI
Rashi writes: "'He commanded them unto Bnei Yisrael' - [I.e.] to lead them gently, and to tolerate them... This is the Midrash." Why does Rashi digress from the simple meaning?
Gur Aryeh: If our verse means simply that Hashem commanded them regarding their mission of bringing the Bnei Yisrael out of Mitzrayim, it ought to specify the details of how they should do so -- at this point in the text, rather than waiting until the next section (7:1-5).
Rashi writes: "'He commanded them unto Bnei Yisrael' - [I.e.] to lead them gently, and to tolerate them." How can this interpretation be read into the Pasuk?
Gur Aryeh: It need not be specified; like a person who tells someone, "I charge you with my son" (i.e. watch over him, take care of him).
Rashi writes: "'He commanded them unto Bnei Yisrael' - [I.e.] to lead them gently, and to tolerate them." How, then, does the end of the Pasuk fit in, "... to take the Bnei Yisrael out of Mitzrayim"?
Gur Aryeh: The verse means, 'As you taking the Bnei Yisrael out from Egypt, you will need to speak to them (as well as before Pharaoh) Be sure to lead them gently (and to speak to Pharaoh with respect).'